Allostatic load is a concept in stress physiology that encompasses the cumulative impact of chronic or repeated stress on the body as it adapts to life's challenges. This concept underscores the intricate connection between mental health and physical well-being, demonstrating that while acute stress is an adaptive response, chronic stress can lead to the overexposure of stress hormones, resulting in various physiological changes that affect overall health. Coined by neuroscientist Bruce McEwen, allostatic load represents the physiological consequences of the body's efforts to adapt to stressors. Its impact varies among individuals due to factors such as personality traits, life experiences, enculturation, and neurobiology. For instance, personalities with higher neuroticism or anxiety sensitivity may be more vulnerable to stress-related health issues. Traumatic events, adverse childhood experiences, cultural factors, and an individual's genetic and epigenetic makeup can all shape their unique allostatic load.